Researchers supported by the Amy Strelzer Manasevit Research Program for the Study of Post-Transplant Complications are listed below.
2013
Amy Strelzer Manasevit Scholar
Ran Reshef, M.D.
Institution: University of Pennsylvania
Project: “Control of Human Graft-Versus-Host Disease by Modulation of Lymphocyte Trafficking”
American Society for Blood and Marrow Transplantation Scholar
Everett H. Meyer, M.D., Ph.D., M.S.
Institution: Stanford University
Project: “Immune Monitoring of Regulatory T Cell Therapy to Treat Steroid Refractory Acute Graft-Versus-Host Disease”
2012
Amy Strelzer Manasevit Scholar
Xiao Chen, M.D., Ph.D.
Institution: Medical College of Wisconsin
Project: “A Critical Role of Retinoic Acid in the Pathophysiology of Gastrointestinal GVHD”
2011
Amy Strelzer Manasevit Scholar
Sophie Paczesny, M.D., Ph.D.
Institution: University of Michigan Medical School
Project: "Proteome of chronic graft versus host disease"
2010
Amy Strelzer Manasevit Scholar
Vu Nguyen, M.D.
Institution: University of Chicago
Project: "Defining the role of gut microflora in graft-versus-host disease"
2009
Amy Strelzer Manasevit Scholar
Stefanie Sarantopoulos, M.D., Ph.D.
Institution: University of North Carolina, Chapel Hill
Project: "The BCR-activated B cell: a novel therapeutic target in chronic GVHD"
2008
Amy Strelzer Manasevit Scholar
Ann M. Leen, B.Sc., Ph.D.
Institution: Baylor College of Medicine
Project: "Multipathogen-specific CTL for the Immunocompromised"
2007
Alaina J. Enlow Scholar
Mari H. Dallas, M.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Project: "Enhanced T Cell Reconstitution by Umbilical Cord Blood Progenitors Expanded Ex-Vivo Using the Notch Ligand Delta 1"
Astellas Post-Doctoral Fellow
Milena Bogunovic, M.D.
Institution: Mount Sinai School of Medicine, New York
Project: "The Role of Recipient Dendritic Cells in Post-Transplant Complications"
2006
Christian Jacobsen Post-Doctoral Fellow
Hong Zheng, M.D., Ph.D.
Institution: Yale University School of Medicine, New Haven, Conn.
Mentor: Warren D. Shlomchik, M.D.
Project: "Spontaneous Memory T Cells in Graft-Versus-Leukemia Effect"
SuperGen Post-Doctoral Fellow
Marie Bleakley, M.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Stanley Riddell, M.D.
Project: "Targeting the Leukemic Stem Cell: Development of a Novel Therapeutic Strategy to Prevent and Treat Leukemic Relapse Following Allogeneic Stem Cell Transplant"
2005
2005 Amy Strelzer Manasevit Scholar and 2006-2007 Jacob and Hilda Blaustein Scholar
Onder S. Alpdogan, M.D.
Institution: Memorial Sloan-Kettering Cancer Center, New York
Mentor: Marcel van den Brink, M.D., Ph.D.
Project: "Immunostimulatory Cytokine/Growth Factor and T Cell Precursor Administration to Enhance Immune Reconstitution after Allogeneic Bone Marrow Transplantation in Experimental Murine Models"
Alaina J. Enlow Scholar
Pavan R. Reddy, M.D.
Institution: University of Michigan Comprehensive Cancer Center, Ann Arbor
Mentor: James Ferrara, M.D.
Project: "Regulation of Acute Graft-Versus-Host Disease and Graft-Versus-Leukemia Effect by Histone Deacetylase Inhibitors"
Baxter Oncology Post-Doctoral Fellow
Cynthia Giver, Ph.D.
Institution: Winship Cancer Institute, Emory University, Atlanta
Mentor: Edmund K. Waller, M.D., Ph.D.
Project: "Fludarabine-Treated Donor T-Cells in Allogeneic BMT-Reduced Graft-Versus-Host Disease Activity with Retained Graft-Versus-Leukemia Effects"
Astellas (Formerly Fujisawa) Post-Doctoral Fellow
William W. Hope, MBBS, FRACP
Institution: National Institutes of Health – National Cancer Institute, Bethesda, Md.
Mentor: Thomas Walsh, M.D.
Project: "The Application of Antifungal Pharmodynamics to Optimize the Therapeutic Outcome of Invasive Aspergillosis Post-Hematopoietic Stem Cell Transplantation"
Christian Jacobsen Post-Doctoral Fellow
Hong Zheng, M.D., Ph.D.
Institution: Yale University School of Medicine, New Haven, Conn.
Mentor: Warren D. Shlomchik, M.D.
Project: "Spontaneous Memory T Cells in Graft-Versus-Leukemia Effect"
SuperGen Post-Doctoral Fellow
Marie Bleakley, M.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Stanley Riddell, M.D.
Project: "Targeting the Leukemic Stem Cell: Development of a Novel Therapeutic Strategy to Prevent and Treat Leukemic Relapse Following Allogeneic Stem Cell Transplant"
2004
Alaina J. Enlow Scholar
Anna Mari Malkki, Ph.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Claudio Anasetti, M.D.
Project: "Identification of Functional Human SNPs in Unrelated Hematopoietic Stem Cells"
Dr. Robert A. Good Scholar
Anthony G. Brickner, Ph.D.
Institution: University of Pittsburgh
Mentor: Albert D. Donnenberg, Ph.D.
Project: "Identifying Graft-Versus-Leukemia-Associated Human Minor Histocompatibility Antigens Restricted by HLA-AZ"
Dr. George Santos Scholar
Jason W. Chien, M.D., M.S.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Joan G. Clark, M.D.
Project: "Bronchiolitis Obliterans Syndrome, Chronic GVHD and the Innate Immune Response"
Baxter Oncology Post-Doctoral Fellow
Lei Bao, M.D., Ph.D.
Institution: University of Minnesota Cancer Center, Minneapolis
Mentor: Dr. Sue Marshall
Project: "Identification of MHC Class II Restricted Male-Specific Human Minor Histocompatibility Antigens for Immunotherapy or Immunoprevention"
SuperGen Post-Doctoral Fellow
Andreas Beilhack, M.D.
Institution: Stanford University, Stanford, Calif.
Mentor: Kathleen Thompson
Project: "The Role of T Cell Trafficking in Graft-Versus-Host Disease"
2003
Amy Strelzer Manasevit Scholars
Catherine M. Bollard, M.D.
Institution: Baylor College of Medicine, Houston
Mentor: Helen Heslop, M.D.
Project: "Adoptive Immunotherapy with Tri-Virus Specific Cytotoxic T Lymphocytes Post Allogeneic Stem Cell Transplant"
Katharine C. Hsu, M.D., Ph.D.
Institution: Memorial Sloan-Kettering Cancer Center, New York
Mentor: Bo DuPont, M.D.
Project: "NK Killer Ig-Like Receptors and Hematopoietic Stem Cell Transplant Outcome"
Baxter Oncology Post-Doctoral Fellow
Kathleen A. Houtchens, Ph.D.
Institution: Children’s Hospital Oakland Research Institute, Oakland, Calif.
Mentor: Elizabeth A. Trachtenberg, Ph.D.
Project: "High Resolution KIR Genotyping System Development and Validation for Use in Post Stem Cell Transplant Outcome Analyses"
SuperGen Post-Doctoral Fellow
Jian-Ming Li, Ph.D.
Institution: Emory University, Atlanta
Mentor: Edmund K. Waller, M.D., Ph.D.
Project: "Immunosuppressive Role of Donor Dendritic Cells in Allogeneic Transplantation"
2002
Amy Strelzer Manasevit Scholars
Kenneth Cooke, M.D. (2002-2003)
Institution: University of Michigan, Ann Arbor
Mentor: James L.M. Ferrara, M.D.
Project: "Cellular and Inflammatory Effectors of Idiopathic Pneumonia Syndrome after Allogeneic Bone Marrow Transplants"
Anna Mari Malkki, Ph.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Claudio Anasetti, M.D.
Project: "Identification of Functional Human SNPs in Unrelated Hematopoietic Stem Cells"
Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) Post-Doctoral Fellow
Jakub Tolar, M.D.
Institution: University of Minnesota, Minneapolis
Mentor: Bruce Blazer, M.D.
Project: "Effect of Multipotent Adult Progenitor Cells on Immune Response after Bone Marrow Transplantation"
2001
Amy Strelzer Manasevit Scholars
Leo Luznik, M.D.
Institution: Johns Hopkins University School of Medicine, Baltimore
Mentors: Ephraim Fuchs, M.D.; Drew Pardoll, M.D.
Project: "Prevention of Relapse with Tumor Vaccines after Allogeneic Bone Marrow Transplant"
Judith Shizuru, M.D., Ph.D.
Institution: Stanford University Medical Center, Stanford, Calif.
Mentors: Karl Blume, M.D.; Irving Weissman, M.D.
Project: "Designing Hematopoietic Grafts to Optimize Post-Transplantation Immune Reconstitution"
Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) Post-Doctoral Fellow
Daniel A. Nikcevich, M.D., Ph.D.
Institution: Duke University, Durham, N.C.
Mentor: Nelson J.A. Chao, M.D.
Project: "A Pilot Study of Unrelated Umbilical Cord Blood Transplantation in Children and Adults with Hematologic Malignancies"
2000
Amy Strelzer Manasevit Scholar
Kenneth Cooke, M.D.
Institution: University of Michigan, Ann Arbor
Mentor: James L.M. Ferrara, M.D.
Project: "Cellular and Inflammatory Effectors of Idiopathic Pneumonia Syndrome after Allogeneic Bone Marrow Transplants"
Jacob and Hilda Blaustein Scholar
Thea Friedman, Ph.D.
Institution: Thomas Jefferson University, Philadelphia
Mentor: Neal Flomenberg, M.D.
Project: "The Use of T-Cell Receptor V-ß Spectratype Analysis in Allogeneic Bone Marrow Transplants"
Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) Post-Doctoral Fellow
Chang-Qing (Mickey) Xun, M.D.
Institution: Fred Hutchinson Cancer Research Center, Seattle
Mentor: Rainer Storb, M.D.
Project: "Non-Cytotoxic Conditioning for Allogeneic Stem Cell Transplants"
1999
Amy Strelzer Manasevit Scholars
Kenneth Lucas, M.D.
Institution: University of Alabama at Birmingham
Mentor: William P. Vaughn, M.D.
Project: "Adoptive Immunotherapy with CMV and EBV Specific Cytotoxic T Lymphocytes Using B Lymphoblastoid Cell Lines"
Marcel Van den Brink, M.D., Ph.D.
Institution: Memorial Sloan-Kettering Cancer Center, New York
Mentor: Richard J. O’Reilly, M.D.
Project: "The Role of FAS Ligand and Perforin in Graft-Versus-Host Disease and Graft-vs-Leukemia after Bone Marrow Transplantation with or without Donor Leukocyte Infusion"
1998
Amy Strelzer Manasevit Scholars
Stephanie Lee, M.D., M.P.H.
Institution: Dana-Farber Cancer Institute, Boston
Mentor: Joseph H. Antin, M.D.
Project: "The Morbidity and Mortality of Chronic Graft-Versus-Host Disease"
Paul Orchard, M.D.
Institution: University of Minnesota, Minneapolis
Mentor: Philip McGlave, M.D.
Project: "Genetic Engineering of T Cells for Unrelated Bone Marrow Transplantation"